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This interaction may induce the activation and nuclear translocation of -catenin, resulting in the transcription of oncogenes (e.g., c-MYC and cyclin D1) to stimulate cells to proliferate and survive

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If you find yourself wanting to switch after every minor plateau or side effect flare, it may be worth exploring whether the desire to alternate reflects a reasonable medical strategy or an anxious response to normal treatment fluctuations

A pilot study suggested that doses above 50 mg/kg could be lethal, setting the highest screening dose for IP injections at 50 mg/kg (456)

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Automated electron microscope tomography using robust prediction of specimen movements